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Tolerance to elevated blood levels varies with the status of the patient.

Information for Patients Inform patients that use of local anesthetics may cause methemoglobinemia, a serious condition that must be treated promptly.

If allowed into the inner lumen, the jelly may dry on the inner surface leaving a residue which tends to clump with flexion, narrowing the lumen.

The importance of a lubricant in transurethral interventions.

In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration.

The entire urethra is evenly coated with lubricant to dilate the tissue.

These changes may be attributable to a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system.

At the first sign of change, oxygen should be administered.

Mutagenesis The mutagenic potential of lidocaine has been tested in the Ames Salmonella reverse mutation assay, an in vitro chromosome aberrations assay in human lymphocytes and in an in vivo mouse micronucleus assay.

How do you pronounce that? Studies of lidocaine metabolism following intravenous bolus injections have shown that the elimination half-life of this agent is typically 1.

These adverse experiences are, in general, dose-related and may result from high plasma levels caused by excessive dosage or rapid absorption, or may result from a hypersensitivity, idiosyncrasy, or diminished tolerance on the part of the patient.